Question

I am a breastfeeding mother and i want to know if it is safe to use CPP 109? Is CPP 109 safe for nursing mother and child? Does CPP 109 extracts into breast milk? Does CPP 109 has any long term or short term side effects on infants? Can CPP 109 influence milk supply or can CPP 109 decrease milk supply in lactating mothers?

CPP 109 lactation summary

CPP 109 is safe in breastfeeding
  • DrLact safety Score for CPP 109 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of CPP 109 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that CPP 109 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of CPP 109 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About CPP 109 usage in lactation

Excreted into breast milk in a clinically non-significant amount. Because of a low oral bioavailability the pass from the breast milk toward the infant's plasma is hampered, except in premature and newborn infants who may exhibit a higher intestinal absorption due to an increased permeability.

Answer by DrLact: About CPP 109 usage in lactation

Limited information indicates that maternal doses of vigabatrin up to 2000 mg daily produce low levels in milk and would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months. Until more data are available, vigabatrin should only be used with careful monitoring during breastfeeding.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.