Question

I am a breastfeeding mother and i want to know if it is safe to use RMI 71754? Is RMI 71754 safe for nursing mother and child? Does RMI 71754 extracts into breast milk? Does RMI 71754 has any long term or short term side effects on infants? Can RMI 71754 influence milk supply or can RMI 71754 decrease milk supply in lactating mothers?

RMI 71754 lactation summary

RMI 71754 is safe in breastfeeding
  • DrLact safety Score for RMI 71754 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of RMI 71754 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that RMI 71754 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of RMI 71754 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About RMI 71754 usage in lactation

Excreted into breast milk in a clinically non-significant amount. Because of a low oral bioavailability the pass from the breast milk toward the infant's plasma is hampered, except in premature and newborn infants who may exhibit a higher intestinal absorption due to an increased permeability.

Answer by DrLact: About RMI 71754 usage in lactation

Limited information indicates that maternal doses of vigabatrin up to 2000 mg daily produce low levels in milk and would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months. Until more data are available, vigabatrin should only be used with careful monitoring during breastfeeding.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.