Is Adapalene Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Adapalene? Is Adapalene safe for nursing mother and child? Does Adapalene extracts into breast milk? Does Adapalene has any long term or short term side effects on infants? Can Adapalene influence milk supply or can Adapalene decrease milk supply in lactating mothers?
Adapalene lactation summary
- DrLact safety Score for Adapalene is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Adapalene is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Adapalene does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Adapalene safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Adapalene usage in lactation
Retinoid analogue with similar properties as Tretinoine. It is practically not absorbed by skin hence it cannot achieve significant levels in the milk. Avoid using it on the breast or cleanse it thoroughly before nursing.
Answer by DrLact: About Adapalene usage in lactation
Topical adapalene has not been studied during breastfeeding. Because it is poorly absorbed after topical application,[1] and blood levels are less than 0.25 mcg/L with long-term use, it is probably a low risk to the nursing infant. Do not apply to the nipple area and ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]
Alternate Drugs
Adapalene(Safe)
Sulfasalazine(Safe)
Olsalazine(Safe)
Mesalamine(Safe)
Antipyrine(Unsafe)
Pimecrolimus(Low Risk)
Apazone(Safe)
Etanercept(Safe)
Butoconazole(Safe)
Salicylic Acid(Safe)
Dexamethasone, Topical(Low Risk)
Benzoyl Peroxide(Safe)
Azelaic Acid(Safe)
Hydroquinone(Low Risk)
Tazarotene(Low Risk)
Adapalene(Safe)
Ustekinumab(Low Risk)
Adalimumab(Safe)
Infliximab(Safe)
Isotretinoin(Unsafe)
Calcipotriene(Safe)
Glycolic Acid(Safe)
Miconazole(Safe)
Tioconazole(Safe)
Ketoconazole(Safe)
Sulconazole(Safe)
Secukinumab(Low Risk)
Erythromycin(Low Risk)
Pimecrolimus(Low Risk)
Tacrolimus(Safe)
Dimethyl fumarate(Low Risk)
Neomycin(Safe)
Oxiconazole(Safe)