Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-MZ1131787D? Is UNII-MZ1131787D safe for nursing mother and child? Does UNII-MZ1131787D extracts into breast milk? Does UNII-MZ1131787D has any long term or short term side effects on infants? Can UNII-MZ1131787D influence milk supply or can UNII-MZ1131787D decrease milk supply in lactating mothers?

UNII-MZ1131787D lactation summary

UNII-MZ1131787D is unsafe in breastfeeding
  • DrLact safety Score for UNII-MZ1131787D is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of UNII-MZ1131787D may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that UNII-MZ1131787D may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using UNII-MZ1131787D .
  • It is recommended to evaluate the advantage of not breastfeeding while using UNII-MZ1131787D Vs not using UNII-MZ1131787D And continue breastfeeding.
  • While using UNII-MZ1131787D Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About UNII-MZ1131787D usage in lactation

Sympathomimetic drug that is topically used for treatment of nose or the eye. On last update no relevant published data related to breastfeeding were found. Nasal use: Avoid high dosing and do not use for longer than 3 days: as an adrenergic agonist drug it could be absorbed and a cause of side effects (vascular hypertension or hypotension, irritability, heart arrhythmia) in both the mother and the infant. Long term maintained doses may decrease milk production. Low risk in Ophthalmologic use: A small dose together with a low plama level of most nasal and ophthalmologic compounds make that a significant excretion into breast milk would be unlikely.

Alternate Drugs for Decongestants & other nasal preparations for topical use. ATC R01A

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