Question

I am a breastfeeding mother and i want to know if it is safe to use HSDB 3293? Is HSDB 3293 safe for nursing mother and child? Does HSDB 3293 extracts into breast milk? Does HSDB 3293 has any long term or short term side effects on infants? Can HSDB 3293 influence milk supply or can HSDB 3293 decrease milk supply in lactating mothers?

HSDB 3293 lactation summary

HSDB 3293 is unsafe in breastfeeding
  • DrLact safety Score for HSDB 3293 is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of HSDB 3293 may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that HSDB 3293 may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using HSDB 3293 .
  • It is recommended to evaluate the advantage of not breastfeeding while using HSDB 3293 Vs not using HSDB 3293 And continue breastfeeding.
  • While using HSDB 3293 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About HSDB 3293 usage in lactation

Thiazide diuretic. Long-term treatment with diuretic drugs (particularly those Thiazides with long lasting effect and loop-acting drugs) may inhibit lactation. Use a lower dose as possible especially during the first postnatal month. Diretic used to supress lactation.

Answer by DrLact: About HSDB 3293 usage in lactation

If HSDB 3293 is required by the mother, it is not a reason to discontinue breastfeeding. Intense diuresis with large doses of HSDB 3293 can decrease breastmilk production, especially during the neonatal period. Shorter-acting diuretics in low doses are preferred over HSDB 3293.

HSDB 3293 Possible Effects in Breastfeeding

HSDB 3293 has been used to suppress lactation in oral doses of 5 mg twice daily for 5 days,[1] and in doses of 10 mg in the morning and 5 mg in the afternoon.[2] The added contribution of the diuretic to these measures, which are effective in suppressing lactation, has not been studied. There are no data on the effects of potent diuretics on established, ongoing lactation.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.