Is Diatrizoate Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Diatrizoate? Is Diatrizoate safe for nursing mother and child? Does Diatrizoate extracts into breast milk? Does Diatrizoate has any long term or short term side effects on infants? Can Diatrizoate influence milk supply or can Diatrizoate decrease milk supply in lactating mothers?

The X-ray contrast media that contain Amidotryzoic acid, Meglumine and Sodium have a content of Iodine from 47% to 62%.Amidotryzoate excretion into breast milk is nil (Fitzjohn, 1982) or in clinically non-significant amount (Texier, 1983: <0.1% of maternal dose) and there have been no problems in infants whose mothers were on this medication. The various Iodinated contrast media for imaging examinations (X-rays, CT scans) are considered compatible with breastfeeding since they are rapidly eliminated with little or no release of iodine, not metabolized and virtually not absorbed when taken by mouth. They are structurally very similar to each other, and some of them have shown no or minimal excretion in the breast milk. Given a low lipoid solubility of the iodinated contrast media, less than 1% of the dose administered to the mother has been found to in the milk.Due to their low oral bioavailability, intestinal absorption is less than 1% of the dose that would be swallowed by the infant.The maximum that is finally got by the baby is less than 0.01% of the maternal dose, which represents less than 1% of the dose administered to an infant who undergoes a radiological contrast examination. Most Scientific Societies of Radiology have agreed that after a radiological iodinated contrast examination is not necessary a temporary weaning of the baby. American Academy of Pediatrics classifies it as usually compatible with breastfeeding medication.WHO List of Essential Medicines 2002 states it is compatible with breastfeeding.

Limited information indicates that maternal doses of diatrizoate up to 38 g (containing 18.5 grams of iodine) produce low levels in milk. In addition, because diatrizoate is poorly absorbed orally, it is not likely to reach the bloodstream of the infant or cause any adverse effects in breastfed infants. Guidelines developed by several professional organizations state that breastfeeding need not be disrupted after a nursing mother receives a iodine-containing contrast medium.[1][2][3][4]