Question

I am a breastfeeding mother and i want to know if it is safe to use Benzathine benzylpenicillin? Is Benzathine benzylpenicillin safe for nursing mother and child? Does Benzathine benzylpenicillin extracts into breast milk? Does Benzathine benzylpenicillin has any long term or short term side effects on infants? Can Benzathine benzylpenicillin influence milk supply or can Benzathine benzylpenicillin decrease milk supply in lactating mothers?

Answer by DrLact: About Benzathine benzylpenicillin usage in lactation

: Limited information indicates Benzathine benzylpenicillin produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with penicillins, but these effects have not been adequately evaluated. Benzathine benzylpenicillin is acceptable in nursing mothers.

Benzathine benzylpenicillin Side Effects in Breastfeeding

A breastfed 1-month-old infant with congenital syphilis developed a Herxheimer reaction 6 hours after its mother received 2.4 million units of Benzathine benzylpenicillin intramuscularly. However, the baby had also received 10 units of penicillin G at about the same time as the mother's injection. The reaction was possibly caused by penicillin in breastmilk.[2]

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