Question

I am a breastfeeding mother and i want to know if it is safe to use Benzylpenicillin benzathine? Is Benzylpenicillin benzathine safe for nursing mother and child? Does Benzylpenicillin benzathine extracts into breast milk? Does Benzylpenicillin benzathine has any long term or short term side effects on infants? Can Benzylpenicillin benzathine influence milk supply or can Benzylpenicillin benzathine decrease milk supply in lactating mothers?

Answer by DrLact: About Benzylpenicillin benzathine usage in lactation

: Limited information indicates Benzylpenicillin benzathine produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with penicillins, but these effects have not been adequately evaluated. Benzylpenicillin benzathine is acceptable in nursing mothers.

Benzylpenicillin benzathine Side Effects in Breastfeeding

A breastfed 1-month-old infant with congenital syphilis developed a Herxheimer reaction 6 hours after its mother received 2.4 million units of Benzylpenicillin benzathine intramuscularly. However, the baby had also received 10 units of penicillin G at about the same time as the mother's injection. The reaction was possibly caused by penicillin in breastmilk.[2]

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