Question

I am a breastfeeding mother and i want to know if it is safe to use NCI-C56100? Is NCI-C56100 safe for nursing mother and child? Does NCI-C56100 extracts into breast milk? Does NCI-C56100 has any long term or short term side effects on infants? Can NCI-C56100 influence milk supply or can NCI-C56100 decrease milk supply in lactating mothers?

Answer by DrLact: About NCI-C56100 usage in lactation

: Limited information indicates NCI-C56100 produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with penicillins, but these effects have not been adequately evaluated. NCI-C56100 is acceptable in nursing mothers.

NCI-C56100 Side Effects in Breastfeeding

A breastfed 1-month-old infant with congenital syphilis developed a Herxheimer reaction 6 hours after its mother received 2.4 million units of NCI-C56100 intramuscularly. However, the baby had also received 10 units of penicillin G at about the same time as the mother's injection. The reaction was possibly caused by penicillin in breastmilk.[2]

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