Question

I am a breastfeeding mother and i want to know if it is safe to use Pendepon? Is Pendepon safe for nursing mother and child? Does Pendepon extracts into breast milk? Does Pendepon has any long term or short term side effects on infants? Can Pendepon influence milk supply or can Pendepon decrease milk supply in lactating mothers?

Answer by DrLact: About Pendepon usage in lactation

: Limited information indicates Pendepon produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with penicillins, but these effects have not been adequately evaluated. Pendepon is acceptable in nursing mothers.

Pendepon Side Effects in Breastfeeding

A breastfed 1-month-old infant with congenital syphilis developed a Herxheimer reaction 6 hours after its mother received 2.4 million units of Pendepon intramuscularly. However, the baby had also received 10 units of penicillin G at about the same time as the mother's injection. The reaction was possibly caused by penicillin in breastmilk.[2]

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