Is P 1393 Safe in Breastfeeding

Question

I am a breastfeeding mother and i want to know if it is safe to use P 1393? Is P 1393 safe for nursing mother and child? Does P 1393 extracts into breast milk? Does P 1393 has any long term or short term side effects on infants? Can P 1393 influence milk supply or can P 1393 decrease milk supply in lactating mothers?

Answer by DrLact: About P 1393 usage in lactation

If P 1393 is required by the mother, it is not a reason to discontinue breastfeeding. Intense diuresis with large doses may decrease breastmilk production.

P 1393 Possible Effects in Breastfeeding

Relevant published information on P 1393 was not found as of the revision date. Intense diuresis with thiazides and thiazide-like diuretics, fluid restriction and breast binding have been used to suppress postpartum lactation.[1][2][3] The added contribution of the diuretic to these measures, which are effective in suppressing lactation, has not been studied. There are no data on the effects of diuretics on established, ongoing lactation.

Alternate Drugs

Nitrendipine(Safe)

Bumetanide(Low Risk)

Bisoprolol(Low Risk)

Guanfacine(Low Risk)

Nisoldipine(Low Risk)

Nitroprusside

Benzthiazide

Atenolol(Unsafe)

Hydrochlorothiazide(Safe)

Guanabenz

Nimodipine(Safe)

Treprostinil

Bosentan(Low Risk)

Acebutolol(Unsafe)

Hydralazine(Safe)

Nicardipine(Safe)

Nifedipine(Safe)

Nebivolol(Unsafe)

Bendroflumethiazide(Unsafe)

Verapamil(Safe)

Furosemide(Low Risk)

Timolol(Safe)

Moexipril

Azilsartan

Benazepril(Safe)

Fosinopril(Low Risk)

Sotalol(Low Risk)

Minoxidil(Safe)

Amlodipine(Low Risk)

Trichlormethiazide

Felodipine(Low Risk)

Propranolol(Safe)

Valsartan(Low Risk)

Trandolapril(Dangerous)

Ethacrynic Acid

Pindolol

Metolazone

Terazosin(Unsafe)

Torsemide(Low Risk)

Enalapril(Safe)

Penbutolol

Methyldopa(Safe)

Telmisartan(Unsafe)

Spironolactone(Safe)

Diltiazem(Safe)

Nadolol(Unsafe)

Prazosin(Unsafe)

Reserpine(Unsafe)

Metoprolol(Safe)

Ramipril(Low Risk)

Lisinopril(Low Risk)

Losartan(Low Risk)

Quinapril

Chlorthalidone(Dangerous)

Levobunolol(Low Risk)

Isradipine(Low Risk)

Irbesartan(Unsafe)

Labetalol(Safe)

Fenoldopam

Polythiazide

Chlorothiazide(Safe)

Esmolol

Indapamide(Low Risk)

Eprosartan(Low Risk)

Perindopril

Captopril(Safe)

Carvedilol(Low Risk)

Doxazosin(Safe)

Benzthiazide

Hydrochlorothiazide(Safe)

Bendroflumethiazide(Unsafe)

Trichlormethiazide

Metolazone

Methyclothiazide

Chlorthalidone(Dangerous)

Polythiazide

Chlorothiazide(Safe)

Indapamide(Low Risk)

Hydroflumethiazide

Synonyms of P 1393

Aquatag

2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3-((benzylthio)methyl)-6-chloro-, 1,1-dioxide

2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(((phenylmethyl)thio)methyl)-, 1,1-dioxide

Benzothiazide

Benzotiazida [INN-Spanish]

Benzthiazidum [INN-Latin]

Benztiazide [DCIT]

3-((Benzylthio)methyl)-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

3-((Benzylthio)methyl)-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide1,1-dioxide

3-Benzylthiomethyl-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide

3-((Benzylthio)methyl)-6-chloro-7-sulfamoyl-2H-benzo-1,2,4-thiadiazine 1,1-dioxide

6-Chloro-3-(((phenylmethyl)thio)methyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

6-Chloro-7-sulfamoyl-3-benzylthiomethyl-2H-1,2,4-benzothiadiazine 1,1-dioxide

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