Question

I am a breastfeeding mother and i want to know if it is safe to use Brompheniraminum [INN-Latin]? Is Brompheniraminum [INN-Latin] safe for nursing mother and child? Does Brompheniraminum [INN-Latin] extracts into breast milk? Does Brompheniraminum [INN-Latin] has any long term or short term side effects on infants? Can Brompheniraminum [INN-Latin] influence milk supply or can Brompheniraminum [INN-Latin] decrease milk supply in lactating mothers?

Brompheniraminum [INN-Latin] lactation summary

Brompheniraminum [INN-Latin] usage has low risk in breastfeeding
  • DrLact safety Score for Brompheniraminum [INN-Latin] is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Brompheniraminum [INN-Latin] may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Brompheniraminum [INN-Latin] may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Brompheniraminum [INN-Latin] low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Brompheniraminum [INN-Latin] We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Brompheniraminum [INN-Latin] usage in lactation

First generation antihistamine, alkylamine drug, sedative with antimuscarinic effect. Described irritability, crying and insomnia in a baby from a nursing mother after taking a preparation compounded by Iso-ephedrine and Brompheniraminum [INN-Latin] that were possibly responsible for the symptoms.Check up the occurrence of drowsiness and inappropriate feeding of the infant. Likely inhibition of breastfeeding in the first weeks after birth due to anti-prolactin effect. It is not recommended bed-sharing with the baby if you are on this medication.

Answer by DrLact: About Brompheniraminum [INN-Latin] usage in lactation

Small, occasional doses of Brompheniraminum [INN-Latin] would not be expected to cause any adverse effects in breastfed infants. Larger doses or more prolonged use may cause effects in the infant or decrease the milk supply, particularly in combination with a sympathomimetic such as pseudoephedrine or before lactation is well established. Single bedtime doses after the last feeding of the day may be adequate for many women and will minimize any effects of the drug. The nonsedating antihistamines are preferred alternatives.

Brompheniraminum [INN-Latin] Side Effects in Breastfeeding

In one telephone follow-up study, mothers reported irritability and colicky symptoms in 10% of infants exposed to various antihistamines and drowsiness was reported in 1.6% of infants. None of the reactions required medical attention and none of the infants were exposed to Brompheniraminum [INN-Latin] or dexBrompheniraminum [INN-Latin].[1]Irritability and disturbed sleep were reported in an 11-week-old breastfed infant whose mother was taking a product containing dexBrompheniraminum [INN-Latin] and etafedrine (d-isoephedrine).[2] These side effects were possibly caused by dexBrompheniraminum [INN-Latin] in breastmilk, but could have been caused by the etafedrine or both drugs.

Brompheniraminum [INN-Latin] Possible Effects in Breastfeeding

Antihistamines in relatively high doses given by injection can decrease basal serum prolactin in nonlactating women and in early postpartum women.[3][4] However, suckling-induced prolactin secretion is not affected by antihistamine pretreatment of postpartum mothers.[3] Whether lower oral doses of Brompheniraminum [INN-Latin] have the same effect on serum prolactin or whether the effects on prolactin have any consequences on breastfeeding success have not been studied. The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.