Question

I am a breastfeeding mother and i want to know if it is safe to use Buspirone? Is Buspirone safe for nursing mother and child? Does Buspirone extracts into breast milk? Does Buspirone has any long term or short term side effects on infants? Can Buspirone influence milk supply or can Buspirone decrease milk supply in lactating mothers?

Answer by DrLact: About Buspirone usage in lactation

Limited information indicates that maternal doses of buspirone up to 45 mg daily produce low levels in milk. Because no information is available on the long-term use of buspirone during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Buspirone Side Effects in Breastfeeding

Possible drug-induced seizure-like activity and cyanosis occurred in a breastfed 3-week-old whose mother was taking buspirone 15 mg 3 times daily as well as fluoxetine and carbamazepine during pregnancy and breastfeeding. The authors thought that this reaction, if drug induced, was most likely caused by fluoxetine.[1] One exclusively breastfed 11-week-old infant was breastfed during maternal therapy with buspirone 10 mg daily and venlafaxine 300 mg daily. No adverse reactions were reported by the mother or in the medical records.[2]

Buspirone Possible Effects in Breastfeeding

Buspirone increases serum prolactin.[3][4][5][6] Galactorrhea was reported in a women taking venlafaxine after buspirone was added to her regimen. However, when buspirone was discontinued, galactorrhea persisted.[7] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.

Alternate Drugs

Oxazepam(Safe)
Nitrazepam(Low Risk)
Midazolam(Safe)
Lorazepam(Safe)
Diazepam(Low Risk)
Meprobamate(Low Risk)
Clorazepate(Low Risk)
Alprazolam(Low Risk)
Temazepam(Low Risk)
Quazepam(Unsafe)
Cisapride(Safe)
Zolmitriptan(Low Risk)
Rizatriptan(Low Risk)
Naratriptan(Low Risk)
Frovatriptan(Low Risk)
Almotriptan(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.