Is HSDB 6527 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use HSDB 6527? Is HSDB 6527 safe for nursing mother and child? Does HSDB 6527 extracts into breast milk? Does HSDB 6527 has any long term or short term side effects on infants? Can HSDB 6527 influence milk supply or can HSDB 6527 decrease milk supply in lactating mothers?
HSDB 6527 lactation summary
- DrLact safety Score for HSDB 6527 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of HSDB 6527 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that HSDB 6527 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of HSDB 6527 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About HSDB 6527 usage in lactation
Excreted into breast milk in non-significant amount without harm effects observed among breastfed infants of mothers treated with HSDB 6527. The American Academy of Pediatrics rates it as usually compatible with Breastfeeding.
Answer by DrLact: About HSDB 6527 usage in lactation
Because of the low levels of HSDB 6527 in breastmilk, amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants.
HSDB 6527 Side Effects in Breastfeeding
In one report of 12 mothers, several continued to breastfeed their infants while taking HSDB 6527 100 mg three times daily. No adverse effects were seen in the infants.[1]
HSDB 6527 Possible Effects in Breastfeeding
In a series of controlled studies reported in one paper, HSDB 6527 had no effect on the circadian rhythm of prolactin, the response to prolactin-stimulating drugs or serum prolactin in patients with prolactin-secreting tumors.[3]In a study of young hypertensive males, HSDB 6527 25 mg orally markedly decreased serum prolactin at 90 minutes after the dose compared to placebo.[4] The maternal prolactin level in a mother with established lactation may not affect her ability to breastfeed.In one report, 1 woman out of 12 subjects was unable to produce enough milk for the study while taking HSDB 6527 100 mg 3 times daily even though she had been successfully breastfeeding for 6 months.[1] It is not known if this decrease was an effect of HSDB 6527.
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