Is (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline? Is (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline safe for nursing mother and child? Does (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline extracts into breast milk? Does (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline has any long term or short term side effects on infants? Can (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline influence milk supply or can (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline decrease milk supply in lactating mothers?
(S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline lactation summary
- DrLact safety Score for (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline usage in lactation
Excreted into breast milk in non-significant amount without harm effects observed among breastfed infants of mothers treated with (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline. The American Academy of Pediatrics rates it as usually compatible with Breastfeeding.
Answer by DrLact: About (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline usage in lactation
Because of the low levels of (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline in breastmilk, amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants.
(S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline Side Effects in Breastfeeding
In one report of 12 mothers, several continued to breastfeed their infants while taking (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline 100 mg three times daily. No adverse effects were seen in the infants.[1]
(S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline Possible Effects in Breastfeeding
In a series of controlled studies reported in one paper, (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline had no effect on the circadian rhythm of prolactin, the response to prolactin-stimulating drugs or serum prolactin in patients with prolactin-secreting tumors.[3]In a study of young hypertensive males, (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline 25 mg orally markedly decreased serum prolactin at 90 minutes after the dose compared to placebo.[4] The maternal prolactin level in a mother with established lactation may not affect her ability to breastfeed.In one report, 1 woman out of 12 subjects was unable to produce enough milk for the study while taking (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline 100 mg 3 times daily even though she had been successfully breastfeeding for 6 months.[1] It is not known if this decrease was an effect of (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline.
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