Question

I am a breastfeeding mother and i want to know if it is safe to use SQ 14225? Is SQ 14225 safe for nursing mother and child? Does SQ 14225 extracts into breast milk? Does SQ 14225 has any long term or short term side effects on infants? Can SQ 14225 influence milk supply or can SQ 14225 decrease milk supply in lactating mothers?

SQ 14225 lactation summary

SQ 14225 is safe in breastfeeding
  • DrLact safety Score for SQ 14225 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of SQ 14225 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that SQ 14225 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of SQ 14225 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About SQ 14225 usage in lactation

Excreted into breast milk in non-significant amount without harm effects observed among breastfed infants of mothers treated with SQ 14225. The American Academy of Pediatrics rates it as usually compatible with Breastfeeding.

Answer by DrLact: About SQ 14225 usage in lactation

Because of the low levels of SQ 14225 in breastmilk, amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants.

SQ 14225 Side Effects in Breastfeeding

In one report of 12 mothers, several continued to breastfeed their infants while taking SQ 14225 100 mg three times daily. No adverse effects were seen in the infants.[1]

SQ 14225 Possible Effects in Breastfeeding

In a series of controlled studies reported in one paper, SQ 14225 had no effect on the circadian rhythm of prolactin, the response to prolactin-stimulating drugs or serum prolactin in patients with prolactin-secreting tumors.[3]In a study of young hypertensive males, SQ 14225 25 mg orally markedly decreased serum prolactin at 90 minutes after the dose compared to placebo.[4] The maternal prolactin level in a mother with established lactation may not affect her ability to breastfeed.In one report, 1 woman out of 12 subjects was unable to produce enough milk for the study while taking SQ 14225 100 mg 3 times daily even though she had been successfully breastfeeding for 6 months.[1] It is not known if this decrease was an effect of SQ 14225.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.