Question

I am a breastfeeding mother and i want to know if it is safe to use N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid? Is N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid safe for nursing mother and child? Does N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid extracts into breast milk? Does N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid has any long term or short term side effects on infants? Can N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid influence milk supply or can N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid decrease milk supply in lactating mothers?

N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid lactation summary

N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid is safe in breastfeeding
  • DrLact safety Score for N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid usage in lactation

Be aware of the possibility of false negative results of bacterial cultures when the mother is on antibiotics.

Answer by DrLact: About N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid usage in lactation

Limited information indicates that carbenicillin produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with penicillins, but these effects have not been adequately evaluated. N-(2-Carboxy-3,3-dimethyl-7-oxo-4-thia-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid is acceptable in nursing mothers.

Alternate Drugs

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Methicillin(Low Risk)
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Cefdinir(Safe)
Indinavir(Unsafe)
Ertapenem(Safe)
Clindamycin(Low Risk)
Gatifloxacin(Low Risk)
Aztreonam(Safe)
Zidovudine(Low Risk)
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Enoxacin(Low Risk)
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Meropenem(Safe)
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Lindane(Unsafe)
Neomycin(Safe)
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Valganciclovir(Low Risk)
Quinine(Safe)
Ganciclovir(Low Risk)
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Saquinavir(Unsafe)
Cefaclor(Safe)
Primaquine(Low Risk)
Didanosine(Unsafe)
Atovaquone(Low Risk)
Levofloxacin(Low Risk)
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Linezolid(Low Risk)
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Moxifloxacin(Low Risk)
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Naftifine(Safe)
Dapsone(Low Risk)
Cefepime(Safe)
Nelfinavir(Unsafe)
Famciclovir(Low Risk)
Amikacin(Safe)
Cefprozil(Safe)
Capreomycin(Low Risk)
Cefdinir(Safe)
Iodine(Unsafe)
Amikacin(Safe)
Ertapenem(Safe)
Clindamycin(Low Risk)
Gatifloxacin(Low Risk)
Methenamine(Unsafe)
Aztreonam(Safe)
Cefazolin(Safe)
Enoxacin(Low Risk)
Cefoxitin(Safe)
Doxycycline(Low Risk)
Cefotetan(Safe)
Neomycin(Safe)
Lomefloxacin(Low Risk)
Nalidixic Acid(Low Risk)
Cefaclor(Safe)
Levofloxacin(Low Risk)
Nafcillin(Safe)
Demeclocycline(Low Risk)
Cefixime(Safe)
Kanamycin(Safe)
Moxifloxacin(Low Risk)
Cefepime(Safe)
Mupirocin(Safe)
Capreomycin(Low Risk)
Cefprozil(Safe)
Ofloxacin(Safe)
Erythromycin(Low Risk)
Methicillin(Low Risk)
Nafcillin(Safe)
Methicillin(Low Risk)
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