Is Gadobenate Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Gadobenate? Is Gadobenate safe for nursing mother and child? Does Gadobenate extracts into breast milk? Does Gadobenate has any long term or short term side effects on infants? Can Gadobenate influence milk supply or can Gadobenate decrease milk supply in lactating mothers?

Gadolinium chelate that has a similar action and use than gadopentetic acid.At latest update no published data on excretion into breast milk were found. It has been used in the pediatric age. The various contrast media that are gadolinium derivatives and used for explorations with Magnetic Resonance Imaging (MRI) are considered compatible with breastfeeding because they are quickly eliminated (elimination half-life of less than 2 hours). They undergo very little metabolic changes and are virtually non-absorbable orally. They are structurally very similar to each other. Some have been shown to have no or minimal excretion into the milk. Less than 0.04% of the dose given to the mother ends just going into the milk.Due to its low oral bioavailability, intestinal absorption should be less than 1% of the dose took by the infant.The maximum dose received by the infant is considered less than 0.0004% of the maternal dose, which is much less than the dose administered to a newborn infant who undergoes a MRI scan. Most Radiology Scientific Societies agree that after an MRI scan is not necessary to temporarily stop breastfeeding. Some authors recommend avoiding the use on lactating women of some Gadolinium contrast media that would pose a high risk for developing Systemic Nephrogenic Fibrosis, especially in the neonatal period, like gadoversetamide, and gadodiamide dimeglumine, by using instead low-risk ones like gadoterate, gadoteridol and gadobutrol.

There is no published experience with gadobenate during breastfeeding. Gadobenate has been safely used in infants, so it does not appear to pose a substantial risk to a breastfed infant.[1] Guidelines developed by several professional organizations state that breastfeeding need not be disrupted after a nursing mother receives a gadolinium-containing contrast medium.[2][3][4]