Is FK 482 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use FK 482? Is FK 482 safe for nursing mother and child? Does FK 482 extracts into breast milk? Does FK 482 has any long term or short term side effects on infants? Can FK 482 influence milk supply or can FK 482 decrease milk supply in lactating mothers?

Third-generation cephalosporin for oral administration. At latest update no published data on excretion into breast milk were found. According to the manufacturer it is not excreted into breast milk (Abbott 2007). Most cephalosporins are excreted into milk in insignificant amounts from a therapeutic point of view without reported complications in infants.Cephalosporins are widely used in the Pediatric practice with a good tolerance, even in the neonatal period, so it is very unlikely that in small amounts through milk would be a cause of problems in the infant. Red discoloration of stools would appear when combined with iron supplements (Lancaster 2008). Be aware of the possibility of false negative results of cultures in febrile infants whose mothers are taking antibiotics as well as the possibility of gastroenteritis (Ito 1993) by altering the intestinal flora.

Although no information is available on the use of FK 482 during breastfeeding, cephalosporins are generally not be expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with cephalosporins, but these effects have not been adequately evaluated. FK 482 is acceptable in nursing mothers.