Question

I am a breastfeeding mother and i want to know if it is safe to use ICI 156834? Is ICI 156834 safe for nursing mother and child? Does ICI 156834 extracts into breast milk? Does ICI 156834 has any long term or short term side effects on infants? Can ICI 156834 influence milk supply or can ICI 156834 decrease milk supply in lactating mothers?

ICI 156834 lactation summary

ICI 156834 is safe in breastfeeding
  • DrLact safety Score for ICI 156834 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of ICI 156834 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that ICI 156834 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of ICI 156834 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About ICI 156834 usage in lactation

Second-generation cephalosporin for injection or parenteral administration. Like most cephalosporins for which data are available, excretion occurs in breast milk in very small amount and it is clinically insignificant (Cho 1982, Novelli 1983, Matsuda 1984). Cephalosporins are widely used in the Pediatric practice with a good tolerance, even in the neonatal period, so it is very unlikely that in small amounts through milk would be a cause of problems in the infant. Be aware of the possibility of false negative results of cultures in febrile infants whose mothers are taking antibiotics as well as the possibility of gastroenteritis (Ito 1993) by altering the intestinal flora.

Answer by DrLact: About ICI 156834 usage in lactation

A moderate amount of information indicates that ICI 156834 produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with cephalosporins, but these effects have not been adequately evaluated. ICI 156834 is acceptable in nursing mothers.

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Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.