Is Ciclesonide Safe in Breastfeeding

Question

I am a breastfeeding mother and i want to know if it is safe to use Ciclesonide? Is Ciclesonide safe for nursing mother and child? Does Ciclesonide extracts into breast milk? Does Ciclesonide has any long term or short term side effects on infants? Can Ciclesonide influence milk supply or can Ciclesonide decrease milk supply in lactating mothers?

Ciclesonide lactation summary

DrLact safety Score for Ciclesonide is 1 out of 8 which is considered Safe as per our analyses.
A safety Score of 1 indicates that usage of Ciclesonide is mostly safe during lactation for breastfed baby.
Our study of different scientific research also indicates that Ciclesonide does not cause any serious side effects in breastfeeding mothers.
Most of scientific studies and research papers declaring usage of Ciclesonide safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Ciclesonide usage in lactation

Since the last update we have not found published data regarding breastfeeding, but its pharmacokinetic characteristics (low systemic absorption, moderately elevated molecular weight, high plasma protein binding and large volume of distribution, AEMPS 2014, FDA 2012) make it very unlikely its excretion into breast milk in significant amounts and its subsequent absorption by the infant. At normal doses it is very rarely absorbed orally or via inhalation (nasal or pulmonary), and does not reach significant levels in plasma (FDA 2012). Experts in breastfeeding and medication consider topical, oral or inhaled corticosteroids to be compatible with breastfeeding (National Asthma Education 2004, Ellsworth 1994, Greenberger 1987).

Answer by DrLact: About Ciclesonide usage in lactation

Although not measured, the amounts of inhaled corticosteroids absorbed into the maternal bloodstream and excreted into breastmilk are probably too small to affect a breastfed infant. Reviewers and an expert panel consider inhaled corticosteroids acceptable to use during breastfeeding.[1][2][3]