Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-48SPP0PA9Q? Is UNII-48SPP0PA9Q safe for nursing mother and child? Does UNII-48SPP0PA9Q extracts into breast milk? Does UNII-48SPP0PA9Q has any long term or short term side effects on infants? Can UNII-48SPP0PA9Q influence milk supply or can UNII-48SPP0PA9Q decrease milk supply in lactating mothers?

UNII-48SPP0PA9Q lactation summary

UNII-48SPP0PA9Q is safe in breastfeeding
  • DrLact safety Score for UNII-48SPP0PA9Q is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of UNII-48SPP0PA9Q is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that UNII-48SPP0PA9Q does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of UNII-48SPP0PA9Q safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About UNII-48SPP0PA9Q usage in lactation

Second-generation cephalosporin for injection or parenteral administration. Like most cephalosporins for which data are available, excretion occurs in breast milk in very small amount and it is clinically insignificant (Cho 1982, Novelli 1983, Matsuda 1984). Cephalosporins are widely used in the Pediatric practice with a good tolerance, even in the neonatal period, so it is very unlikely that in small amounts through milk would be a cause of problems in the infant. Be aware of the possibility of false negative results of cultures in febrile infants whose mothers are taking antibiotics as well as the possibility of gastroenteritis (Ito 1993) by altering the intestinal flora.

Answer by DrLact: About UNII-48SPP0PA9Q usage in lactation

A moderate amount of information indicates that UNII-48SPP0PA9Q produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with cephalosporins, but these effects have not been adequately evaluated. UNII-48SPP0PA9Q is acceptable in nursing mothers.

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Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.