Question

I am a breastfeeding mother and i want to know if it is safe to use U-76,253A? Is U-76,253A safe for nursing mother and child? Does U-76,253A extracts into breast milk? Does U-76,253A has any long term or short term side effects on infants? Can U-76,253A influence milk supply or can U-76,253A decrease milk supply in lactating mothers?

Answer by DrLact: About U-76,253A usage in lactation

Limited information indicates that U-76,253A produces low levels in milk and is not be expected to cause any adverse effects in breastfed infants.. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with cephalosporins, but these effects have not been adequately evaluated. U-76,253A is acceptable in nursing mothers.

U-76,253A Possible Effects in Breastfeeding

Hyperprolactinemia and bilateral galactorrhea occurred in a nonpregnant, 40-year-old woman taking U-76,253A 200 mg twice daily for 2 days. Seven days after stopping the drug, galactorrhea ceased and the serum prolactin dropped markedly into the normal range. One month later it had dropped further. Because no other cause could be found, the authors determined that the galactorrhea and hyperprolactinemia were probably caused by U-76,253A.[1] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.

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