Question

I am a breastfeeding mother and i want to know if it is safe to use Interferon Gamma-1b? Is Interferon Gamma-1b safe for nursing mother and child? Does Interferon Gamma-1b extracts into breast milk? Does Interferon Gamma-1b has any long term or short term side effects on infants? Can Interferon Gamma-1b influence milk supply or can Interferon Gamma-1b decrease milk supply in lactating mothers?

Answer by DrLact: About Interferon Gamma-1b usage in lactation

Interferon gamma is a normal component of human milk. No data are available on the use of exogenous interferon gamma 1b during breastfeeding. However, the amounts of the similar drugs, interferon alfa and interferon beta-1a, excreted into milk are very low. Any interferon in breastmilk is probably destroyed in the infant's gastrointestinal tract and not absorbed, except perhaps in neonates. Holder pasteurization (62.5 degrees C for 30 minutes) decreases the concentration of endogenous interferon-gamma by an average about 10%.[1]

Alternate Drugs

Durvalumab
Avelumab
Dupilumab
Ocrelizumab
Atezolizumab
Peginterferon Beta
Pembrolizumab
Nivolumab(Unsafe)
Ipilimumab(Unsafe)
Interferon Alfacon-1
Interferon Gamma-1b
Interferon Beta
Glatiramer(Low Risk)

Synonyms of Interferon Gamma-1b

Actimmune
Interferon gamma-1b, recombinant
gamma Interferon 1B
IFN-gamma 1b
Interferon Gamma 1-b
UNII-21K6M2I7AG
HSDB 8137
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