Is RU 51746 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use RU 51746? Is RU 51746 safe for nursing mother and child? Does RU 51746 extracts into breast milk? Does RU 51746 has any long term or short term side effects on infants? Can RU 51746 influence milk supply or can RU 51746 decrease milk supply in lactating mothers?
Answer by DrLact: About RU 51746 usage in lactation
Limited information indicates that RU 51746 produces low levels in milk and is not be expected to cause any adverse effects in breastfed infants.. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with cephalosporins, but these effects have not been adequately evaluated. RU 51746 is acceptable in nursing mothers.
RU 51746 Possible Effects in Breastfeeding
Hyperprolactinemia and bilateral galactorrhea occurred in a nonpregnant, 40-year-old woman taking RU 51746 200 mg twice daily for 2 days. Seven days after stopping the drug, galactorrhea ceased and the serum prolactin dropped markedly into the normal range. One month later it had dropped further. Because no other cause could be found, the authors determined that the galactorrhea and hyperprolactinemia were probably caused by RU 51746.[1] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
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