Is Antipyrine Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Antipyrine? Is Antipyrine safe for nursing mother and child? Does Antipyrine extracts into breast milk? Does Antipyrine has any long term or short term side effects on infants? Can Antipyrine influence milk supply or can Antipyrine decrease milk supply in lactating mothers?

• DrLact safety Score for Antipyrine is 5 out of 8 which is considered Unsafe as per our analyses.
• A safety Score of 5 indicates that usage of Antipyrine may cause serious side effects in breastfed baby.
• Our study of different scientific research indicates that Antipyrine may cause moderate to high side effects or may affect milk supply in lactating mother.
• Our suggestion is to use safer alternate options rather than using Antipyrine .
• It is recommended to evaluate the advantage of not breastfeeding while using Antipyrine Vs not using Antipyrine And continue breastfeeding.
• While using Antipyrine Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
• Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Pyrazolone derivative analgesic that inhibits Prostaglandin synthesis with an increased risk of medullar aplasia. Multiple compounds in association to caffeine, codeine, atropine and anti-inflammatory drugs are available. Overall, multi-drug associated compounds are not recommended especially while nursing. A single drug product should be .preferred. Ear drops containing this component are safe while nursing.

Antipyrine is considered unlikely to harm the infant.[1] Because antipyrine is available only in ear drops, it is unlikely to be absorbed by the mother and reach the breastmilk. No special precautions are required during maternal use of antipyrine-containing ear drops.