Question

I am a breastfeeding mother and i want to know if it is safe to use Artesunate? Is Artesunate safe for nursing mother and child? Does Artesunate extracts into breast milk? Does Artesunate has any long term or short term side effects on infants? Can Artesunate influence milk supply or can Artesunate decrease milk supply in lactating mothers?

Artesunate lactation summary

Artesunate is safe in breastfeeding
  • DrLact safety Score for Artesunate is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Artesunate is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Artesunate does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Artesunate safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Artesunate usage in lactation

Extracted from Artemisia annua a plant that is used in China for malaria treatment. It has been included in WHO’s Model List of Essential Drug and considered a suitable medication during breastfeeding. Extraídos de la Artemisia annua, planta utilizada en China contra el paludismo. Considerada medicación esencial compatible con la lactancia por la OMS. Se utiliza asociado a lumefantrina (Coartem) para el tratamiento del paludismo por plasmodium falciparum sin complicaciones.

Answer by DrLact: About Artesunate usage in lactation

Limited information indicates that a maternal dose of 200 mg orally produced low levels in milk and would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months. Withholding breastfeeding for 6 hour after a dose should markedly reduce the dose the infant receives. In general, very small amounts of antimalarial drugs are excreted in the breast milk of lactating women. Because the quantity of antimalarial drugs transferred in breast milk is insufficient to provide adequate protection against malaria, infants who require chemoprophylaxis must receive the recommended dosages of antimalarial drugs.[1]

Artesunate Side Effects in Breastfeeding

Breastfed infants who were given dihydroartemisinin and piperaquine as a treatment for malaria had a higher frequency of vomiting than non-breastfed infants given the drugs. Whether this finding applies to infants who receive dihydroartemisinin via breastmilk has not been studied.[3]

Alternate Drugs

Valganciclovir(Low Risk)
Amantadine(Low Risk)
Tenofovir(Safe)
Amikacin(Safe)
Neomycin(Safe)
Ganciclovir(Low Risk)
Cefixime(Safe)
Demeclocycline(Low Risk)
Nafcillin(Safe)
Cefepime(Safe)
Efavirenz(Unsafe)
Econazole(Safe)
Moxifloxacin(Low Risk)
Primaquine(Low Risk)
Didanosine(Unsafe)
Lindane(Unsafe)
Malathion(Low Risk)
Cefdinir(Safe)
Saquinavir(Unsafe)
Methicillin(Low Risk)
Cefazolin(Safe)
Meropenem(Safe)
Ritonavir(Unsafe)
Cefaclor(Safe)
Abacavir(Safe)
Lomefloxacin(Low Risk)
Atovaquone(Low Risk)
Famciclovir(Low Risk)
Nevirapine(Low Risk)
Levofloxacin(Low Risk)
Linezolid(Low Risk)
Erythromycin(Low Risk)
Nelfinavir(Unsafe)
Kanamycin(Safe)
Clindamycin(Low Risk)
Naftifine(Safe)
Cefprozil(Safe)
Aztreonam(Safe)
Capreomycin(Low Risk)
Dapsone(Low Risk)
Acyclovir(Safe)
Cefoxitin(Safe)
Indinavir(Unsafe)
Rifaximin(Safe)
Gatifloxacin(Low Risk)
Ertapenem(Safe)
Ofloxacin(Safe)
Cefotetan(Safe)
Enoxacin(Low Risk)
Zidovudine(Low Risk)
Doxycycline(Low Risk)
Quinine(Safe)
Primaquine(Low Risk)
Atovaquone(Low Risk)
Quinine(Safe)
Primaquine(Low Risk)
Pyrantel(Safe)
Lindane(Unsafe)
Malathion(Low Risk)
Atovaquone(Low Risk)
Quinine(Safe)
Atovaquone(Low Risk)
Quinine(Safe)
Primaquine(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.