Is 4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use 4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide? Is 4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide safe for nursing mother and child? Does 4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide extracts into breast milk? Does 4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide has any long term or short term side effects on infants? Can 4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide influence milk supply or can 4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide decrease milk supply in lactating mothers?
4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide lactation summary
- DrLact safety Score for 4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of 4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that 4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of 4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About 4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide usage in lactation
Indicated for treatment of Arthritis, Arthrosis and Gout. Acts by blocking cyclooxygenase enzyme (COX-2) The amount of drug excreted into breast milk is so low that even trace amounts have not been found in blood sera of breastfed infant from treated mothers.
Answer by DrLact: About 4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide usage in lactation
Because of the low levels of 4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide in breastmilk, amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants.[1] No special precautions are required.
4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide Side Effects in Breastfeeding
No infant side effects were noted by the mothers of 2 infants aged 17 and 22 months who were breastfed during long-term maternal use of 4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide 200 mg daily.[3]
Alternate Drugs
Ketorolac(Safe)
Tolmetin(Safe)
Celecoxib(Safe)
Indomethacin(Safe)
Sulindac(Low Risk)
Ibuprofen(Safe)
Piroxicam(Safe)
Flurbiprofen(Safe)
Naproxen(Low Risk)
Dipyrone(Low Risk)
Nabumetone(Low Risk)
Ketoprofen(Safe)
Fenoprofen(Safe)
Meloxicam(Low Risk)
Aspirin(Low Risk)
Etodolac(Low Risk)
Mefenamic Acid(Safe)
Oxaprozin(Low Risk)
Diflunisal(Low Risk)
Meclofenamate(Low Risk)
Diclofenac(Safe)
Ketorolac(Safe)
Tolmetin(Safe)
Celecoxib(Safe)
Indomethacin(Safe)
Sulindac(Low Risk)
Ibuprofen(Safe)
Piroxicam(Safe)
Flurbiprofen(Safe)
Naproxen(Low Risk)
Dipyrone(Low Risk)
Nabumetone(Low Risk)
Ketoprofen(Safe)
Fenoprofen(Safe)
Meloxicam(Low Risk)
Aspirin(Low Risk)
Etodolac(Low Risk)
Mefenamic Acid(Safe)
Oxaprozin(Low Risk)
Diflunisal(Low Risk)
Meclofenamate(Low Risk)
Diclofenac(Safe)