Question

I am a breastfeeding mother and i want to know if it is safe to use Atovaquone and Proquanil? Is Atovaquone and Proquanil safe for nursing mother and child? Does Atovaquone and Proquanil extracts into breast milk? Does Atovaquone and Proquanil has any long term or short term side effects on infants? Can Atovaquone and Proquanil influence milk supply or can Atovaquone and Proquanil decrease milk supply in lactating mothers?

Answer by DrLact: About Atovaquone and Proquanil usage in lactation

No information is available on the use of atovaquone and proguanil during breastfeeding. The Centers for Disease Control and Prevention does not currently recommend it for the prevention of malaria in women breastfeeding infants weighing less than 5 kg (11 pounds). However, it can be used for treatment of women who are breastfeeding infants of any weight when the potential benefit outweighs the potential risk to the infant (e.g., treating a breastfeeding woman who has acquired malaria in an area of multidrug-resistant strains and who cannot tolerate other treatment options).[1] In general, very small amounts of antimalarial drugs are excreted in the breast milk of lactating women. Because the quantity of antimalarial drugs transferred in breast milk is insufficient to provide adequate protection against malaria, infants who require chemoprophylaxis must also receive the recommended dosages of antimalarial drugs.[1]

Alternate Drugs

Ritonavir(Unsafe)
Lomefloxacin(Low Risk)
Atovaquone(Low Risk)
Famciclovir(Low Risk)
Cefaclor(Safe)
Abacavir(Safe)
Nevirapine(Low Risk)
Levofloxacin(Low Risk)
Linezolid(Low Risk)
Erythromycin(Low Risk)
Nelfinavir(Unsafe)
Kanamycin(Safe)
Clindamycin(Low Risk)
Naftifine(Safe)
Cefprozil(Safe)
Aztreonam(Safe)
Capreomycin(Low Risk)
Dapsone(Low Risk)
Acyclovir(Safe)
Cefoxitin(Safe)
Indinavir(Unsafe)
Rifaximin(Safe)
Gatifloxacin(Low Risk)
Ertapenem(Safe)
Cefotetan(Safe)
Enoxacin(Low Risk)
Zidovudine(Low Risk)
Ofloxacin(Safe)
Doxycycline(Low Risk)
Quinine(Safe)
Valganciclovir(Low Risk)
Amantadine(Low Risk)
Tenofovir(Safe)
Amikacin(Safe)
Neomycin(Safe)
Cefixime(Safe)
Demeclocycline(Low Risk)
Nafcillin(Safe)
Ganciclovir(Low Risk)
Cefepime(Safe)
Efavirenz(Unsafe)
Econazole(Safe)
Moxifloxacin(Low Risk)
Primaquine(Low Risk)
Didanosine(Unsafe)
Lindane(Unsafe)
Malathion(Low Risk)
Cefdinir(Safe)
Saquinavir(Unsafe)
Methicillin(Low Risk)
Cefazolin(Safe)
Meropenem(Safe)
Quinine(Safe)
Primaquine(Low Risk)
Atovaquone(Low Risk)
Atovaquone(Low Risk)
Quinine(Safe)
Primaquine(Low Risk)
Pyrantel(Safe)
Lindane(Unsafe)
Malathion(Low Risk)
Quinine(Safe)
Primaquine(Low Risk)
Atovaquone(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.