Is Glycopyrrolate Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Glycopyrrolate? Is Glycopyrrolate safe for nursing mother and child? Does Glycopyrrolate extracts into breast milk? Does Glycopyrrolate has any long term or short term side effects on infants? Can Glycopyrrolate influence milk supply or can Glycopyrrolate decrease milk supply in lactating mothers?

• DrLact safety Score for Glycopyrrolate is 5 out of 8 which is considered Unsafe as per our analyses.
• A safety Score of 5 indicates that usage of Glycopyrrolate may cause serious side effects in breastfed baby.
• Our study of different scientific research indicates that Glycopyrrolate may cause moderate to high side effects or may affect milk supply in lactating mother.
• Our suggestion is to use safer alternate options rather than using Glycopyrrolate .
• It is recommended to evaluate the advantage of not breastfeeding while using Glycopyrrolate Vs not using Glycopyrrolate And continue breastfeeding.
• While using Glycopyrrolate Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
• Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Use minimal dosage. Do not use on a long-term basis since anti-cholinergic drugs may decrease milk production. Not commercially available in Spain

No information is available on the use of glycopyrrolate during breastfeeding. Because glycopyrrolate is a quaternary ammonium compound, it is not likely to be absorbed and reach the bloodstream of the infant,[1][2][3] especially when given by inhalation or topically on the skin. Long-term oral use of glycopyrrolate might reduce milk production or milk letdown, but a single dose is unlikely to interfere with breastfeeding. During long-term use, observe for signs of decreased lactation (e.g., insatiety, poor weight gain).

Relevant published information in nursing mothers was not found as of the revision date. Anticholinergics can inhibit lactation in animals, apparently by inhibiting growth hormone and oxytocin secretion.[4][5][6][7][8] Anticholinergic drugs can also reduce serum prolactin in nonnursing women.[9] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.