Question

I am a breastfeeding mother and i want to know if it is safe to use Ipratropium? Is Ipratropium safe for nursing mother and child? Does Ipratropium extracts into breast milk? Does Ipratropium has any long term or short term side effects on infants? Can Ipratropium influence milk supply or can Ipratropium decrease milk supply in lactating mothers?

Ipratropium lactation summary

Ipratropium is safe in breastfeeding
  • DrLact safety Score for Ipratropium is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Ipratropium is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Ipratropium does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Ipratropium safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Ipratropium usage in lactation

At latest update no published data on excretion into breastmilk were found.

 Because of a large volume of distribution along with a very low or undetectable plasma concentration reached after inhalation (Laurikainen 1988, Wood 1995), it must be very unlikely the passage of significant amounts into breastmilk.
Its low oral bioavailability would hamper the pass to the infant’s plasma through the breastmilk ingested.
It has been used to treat newborns (Pediamecum 2015). 

Experts and scientific societies consider the use of ipratropium bromide during breastfeeding as devoid of risk to the infant (van Haren 1998, National Asthma Education 2004, Amir 2011).

Answer by DrLact: About Ipratropium usage in lactation

Although no published data exist on the use of ipratropium, its use produces negligible maternal serum levels and any drug in breastmilk would not be absorbed by the infant. The risk to the breastfed infant of maternal ipratropium inhalation is small.

Alternate Drugs

Arfomoterol(Low Risk)
Zafirlukast(Low Risk)
Albuterol(Safe)
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Cromolyn(Safe)
Arfomoterol(Low Risk)
Albuterol(Safe)
Atropine(Safe)
Cyclopentolate(Low Risk)
Tolterodine(Low Risk)
Solifenacin(Unsafe)
Oxybutinyn(Low Risk)
Atropine(Safe)
Flavoxate(Low Risk)
Dicyclomine(Unsafe)
Scopolamine(Low Risk)
Tropicamide(Low Risk)
Fesoterodine(Low Risk)
Tolterodine(Low Risk)
Solifenacin(Unsafe)
Oxybutinyn(Low Risk)
Atropine(Safe)
Flavoxate(Low Risk)
Dicyclomine(Unsafe)
Scopolamine(Low Risk)
Tropicamide(Low Risk)
Fesoterodine(Low Risk)
Cyclopentolate(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.