I am a breastfeeding mother and i want to know if it is safe to use Cisapride? Is Cisapride safe for nursing mother and child? Does Cisapride extracts into breast milk? Does Cisapride has any long term or short term side effects on infants? Can Cisapride influence milk supply or can Cisapride decrease milk supply in lactating mothers?

Cisapride lactation summary

Cisapride is safe in breastfeeding
  • DrLact safety Score for Cisapride is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Cisapride is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Cisapride does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Cisapride safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Cisapride usage in lactation

It is excreted into breast milk in clinically non-significant amount. No problems attributable to this drug have been observed among infants whose mothers were receiving this medication. It may cause an increase of prolactin secretion. American Academy of Pediatrics states that it is a medication usually compatible with breastfeeding. Because of the high risk of QT-interval prolongation and cardiac arrhythmias in patients who are taking it, especially if other medicines are associated or patients are affected by other conditions, it has been withdrawn from the market in many countries.

Answer by DrLact: About Cisapride usage in lactation

Cisapride was removed from the market in the United States by the U.S. Food and Drug Administration because of cardiac toxicity. Because of the low levels of cisapride in breastmilk, its use is acceptable in nursing mothers if it is required.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.