Question

I am a breastfeeding mother and i want to know if it is safe to use NCI-C01752? Is NCI-C01752 safe for nursing mother and child? Does NCI-C01752 extracts into breast milk? Does NCI-C01752 has any long term or short term side effects on infants? Can NCI-C01752 influence milk supply or can NCI-C01752 decrease milk supply in lactating mothers?

NCI-C01752 lactation summary

NCI-C01752 usage has low risk in breastfeeding
  • DrLact safety Score for NCI-C01752 is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of NCI-C01752 may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that NCI-C01752 may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of NCI-C01752 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using NCI-C01752 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About NCI-C01752 usage in lactation

Sulfonilurea drugs stimulate secretion of endogen insulin. Oral anti-diabetic drugs are useless for treatment of diabetes type 1. For diabetes type 2, diet and exercise are advisable. Breastfeeding helps to lower glucemia level. See section on Maternal diabetes mellitus

Answer by DrLact: About NCI-C01752 usage in lactation

Limited data indicate that amounts of NCI-C01752 in breastmilk are unlikely to affect a breastfed infant. Short-acting drugs are generally preferred while breastfeeding a neonate to avoid drug accumulation. Monitor breastfed infants for signs of hypoglycemia such as jitteriness, excessive sleepiness, poor feeding, seizures cyanosis, apnea, or hypothermia. If there is concern, monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with hypoglycemic agents.[1][2]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.