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Drug safty at a glance


Question

I am a breastfeeding mother and i want to know if it is safe to use Ketoprofen? Is Ketoprofen safe for nursing mother and child? Does Ketoprofen extracts into breast milk? Does Ketoprofen has any long term or short term side effects on infants? Can Ketoprofen influence milk supply or can Ketoprofen decrease milk supply in lactating mothers?

Ketoprofen lactation summary

Ketoprofen is safe in breastfeeding
  • DrLact safety Score for Ketoprofen is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Ketoprofen is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Ketoprofen does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Ketoprofen safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Ketoprofen usage in lactation

Ketoprofen is excreted into breast milk in non-significant amount. Hence, reportedly gastrointestinal side effects on breastfed infants are hardly believable. When apply on skin systemic absorption is very low.

Answer by DrLact: About Ketoprofen usage in lactation

Although ketoprofen has low levels in breastmilk, one center reported that they had received reports of adverse renal and gastrointestinal side effects in breastfed infants whose mothers were taking ketoprofen. Other agents are preferred, especially while nursing a newborn or preterm infant.

Ketoprofen Side Effects in Breastfeeding

All adverse reactions in breastfed infants reported in France between January 1985 and June 2011 were compiled by a French pharmacovigilance center. Of 174 reports, ketoprofen was reported to cause adverse reactions in 8 infants and to be one of the drugs most often suspected in serious adverse reactions, such as esophageal ulceration, erosive gastritis, meningeal hemorrhage, and renal insufficiency.[2]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.