Question

I am a breastfeeding mother and i want to know if it is safe to use 5-25-11-00364 (Beilstein Handbook Reference)? Is 5-25-11-00364 (Beilstein Handbook Reference) safe for nursing mother and child? Does 5-25-11-00364 (Beilstein Handbook Reference) extracts into breast milk? Does 5-25-11-00364 (Beilstein Handbook Reference) has any long term or short term side effects on infants? Can 5-25-11-00364 (Beilstein Handbook Reference) influence milk supply or can 5-25-11-00364 (Beilstein Handbook Reference) decrease milk supply in lactating mothers?

5-25-11-00364 (Beilstein Handbook Reference) lactation summary

5-25-11-00364 (Beilstein Handbook Reference) usage has low risk in breastfeeding
  • DrLact safety Score for 5-25-11-00364 (Beilstein Handbook Reference) is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of 5-25-11-00364 (Beilstein Handbook Reference) may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that 5-25-11-00364 (Beilstein Handbook Reference) may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of 5-25-11-00364 (Beilstein Handbook Reference) low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using 5-25-11-00364 (Beilstein Handbook Reference) We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About 5-25-11-00364 (Beilstein Handbook Reference) usage in lactation

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Answer by DrLact: About 5-25-11-00364 (Beilstein Handbook Reference) usage in lactation

Because there is little published experience with 5-25-11-00364 (Beilstein Handbook Reference) during breastfeeding, and sedation and adverse hematologic effects have been reported in breastfed infants, other agents are preferred.[1] If breastfeeding is undertaken by a mother who is taking 5-25-11-00364 (Beilstein Handbook Reference), close monitoring of the infant for excessive sedation and periodic monitoring of the infant's white blood cell count is advisable. Several authoritative sources recommend that women taking 5-25-11-00364 (Beilstein Handbook Reference) not breastfeed.[2][3][4]

5-25-11-00364 (Beilstein Handbook Reference) Side Effects in Breastfeeding

Among 4 infants who were breastfed by mothers taking 5-25-11-00364 (Beilstein Handbook Reference), 1 infant experienced drowsiness and 1 infant experienced agranulocytosis possibly caused by 5-25-11-00364 (Beilstein Handbook Reference). Details of the cases are lacking.[7] A healthy female infant was born to a mother who took 5-25-11-00364 (Beilstein Handbook Reference) 100 mg daily throughout pregnancy and lactation. She was breastfed (extent not stated) up to 1 year of age. The infant developed normally except for speech which was delayed considerably. She did not achieve normal, fluent speech until the age of 5 years. The delayed speech development was possibly related to 5-25-11-00364 (Beilstein Handbook Reference) in breastmilk, but it could have been the result of exposure to the drug during gestation or could have been unrelated to 5-25-11-00364 (Beilstein Handbook Reference).[8] One woman who took 5-25-11-00364 (Beilstein Handbook Reference) 100 mg daily in late pregnancy and postpartum partially breastfed her infant for 5 days. No neurodevelopmental disorders were detected in the infant after 32 months of follow-up.[6]

5-25-11-00364 (Beilstein Handbook Reference) Possible Effects in Breastfeeding

Unlike the phenothiazines, 5-25-11-00364 (Beilstein Handbook Reference) has a minimal effect on maternal serum prolactin levels.[9][10] However, a woman who had been taking 5-25-11-00364 (Beilstein Handbook Reference) plus high-dose haloperidol developed hyperprolactinemia and severe galactorrhea 2 weeks after stopping haloperidol and 4 days after starting valproic acid. A dose of cabergoline normalized her serum prolactin and galactorrhea ceased for the following 2 months of observation.[11] The maternal prolactin level in a mother with established lactation may not affect her ability to breastfeed.
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