Question

I am a breastfeeding mother and i want to know if it is safe to use HSDB 3051? Is HSDB 3051 safe for nursing mother and child? Does HSDB 3051 extracts into breast milk? Does HSDB 3051 has any long term or short term side effects on infants? Can HSDB 3051 influence milk supply or can HSDB 3051 decrease milk supply in lactating mothers?

HSDB 3051 lactation summary

HSDB 3051 usage has low risk in breastfeeding
  • DrLact safety Score for HSDB 3051 is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of HSDB 3051 may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that HSDB 3051 may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of HSDB 3051 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using HSDB 3051 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About HSDB 3051 usage in lactation

Although it is secreted into breast milk it has not been detected in infant’s blood because it forms unabsorbable chelate compounds with milk calcium. It is not recommended a long-term use (more than 3-4 weeks) since damage on bone growth plates, teeth discoloration, or alteration of intestinal flora may occur. Be aware of the possibility of false negative results of bacterial cultures when the mother is on antibiotics. Withdrawn from the market in Spain.

Answer by DrLact: About HSDB 3051 usage in lactation

A number of reviews have stated that tetracyclines are contraindicated during breastfeeding because of possible staining of infants' dental enamel or bone deposition of tetracyclines. However, a close examination of available literature indicates that there is not likely to be harm in short-term use of HSDB 3051 during lactation because milk levels are low and absorption by the infant is inhibited by the calcium in breastmilk. Short-term use of HSDB 3051 is acceptable in nursing mothers. As a theoretical precaution, avoid prolonged or repeat courses during nursing. Monitor the infant for rash and for possible effects on the gastrointestinal flora, such as diarrhea or candidiasis (thrush, diaper rash).

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Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.