Is Denosin Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Denosin? Is Denosin safe for nursing mother and child? Does Denosin extracts into breast milk? Does Denosin has any long term or short term side effects on infants? Can Denosin influence milk supply or can Denosin decrease milk supply in lactating mothers?

Second generation anti-histaminic and piperidine drug with mild sedative effect. Active metabolite of loratadine. Loratadine is excreted in non-significant amount into breast milk. No side effects were observed in breastfed infants of treated mothers. The British Society of Immunology and Allergy rates it compatible with breastfeeding. The American Academy of Pediatrics rates it compatible with breastfeeding.

Because of its expected low milk levels and lack of sedation and anticholinergic effects, maternal use of Denosin is unlikely to affect a breastfed infant or milk production. Denosin might have a negative effect on lactation in combination with a sympathomimetic agent such as pseudoephedrine.

Antihistamines in relatively high doses given by injection can decrease basal serum prolactin in nonlactating women and in early postpartum women.[2][3] However, suckling-induced prolactin secretion is not affected by antihistamine pretreatment of postpartum mothers.[2] Whether lower oral doses of antihistamines have the same effect on serum prolactin or whether the effects on prolactin have any consequences on breastfeeding success have not been studied. The prolactin level in a mother with established lactation may not affect her ability to breastfeed.