Is Chlorpropamide Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Chlorpropamide? Is Chlorpropamide safe for nursing mother and child? Does Chlorpropamide extracts into breast milk? Does Chlorpropamide has any long term or short term side effects on infants? Can Chlorpropamide influence milk supply or can Chlorpropamide decrease milk supply in lactating mothers?
Chlorpropamide lactation summary
- DrLact safety Score for Chlorpropamide is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Chlorpropamide may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Chlorpropamide may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Chlorpropamide low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Chlorpropamide We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Chlorpropamide usage in lactation
Sulfonilurea drugs stimulate secretion of endogen insulin. Oral anti-diabetic drugs are useless for treatment of diabetes type 1. For diabetes type 2, diet and exercise are advisable. Breastfeeding helps to lower glucemia level. See section on Maternal diabetes mellitus
Answer by DrLact: About Chlorpropamide usage in lactation
Limited data indicate that amounts of chlorpropamide in breastmilk are unlikely to affect a breastfed infant. Short-acting drugs are generally preferred while breastfeeding a neonate to avoid drug accumulation. Monitor breastfed infants for signs of hypoglycemia such as jitteriness, excessive sleepiness, poor feeding, seizures cyanosis, apnea, or hypothermia. If there is concern, monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with hypoglycemic agents.[1][2]
Alternate Drugs
Pioglitazone(Low Risk)
Empagliflozin(Unsafe)
Nateglinide(Unsafe)
Dapagliflozin(Unsafe)
Metformin(Safe)
Alogliptin(Low Risk)
Insulin(Safe)
Linagliptin(Low Risk)
Glyburide(Safe)
Sitagliptin(Low Risk)
Saxagliptin(Low Risk)
Glipizide(Safe)
Colesevelam(Safe)
Miglitol(Safe)
Glimepiride(Unsafe)
Dulaglutide(Low Risk)
Chlorpropamide(Low Risk)
Tolbutamide(Safe)
Liraglutide(Low Risk)
Acetohexamide(Low Risk)
Acarbose(Safe)
Rosiglitazone(Low Risk)
Repaglinide(Unsafe)
Glyburide(Safe)
Glipizide(Safe)
Glimepiride(Unsafe)
Tolbutamide(Safe)
Chlorpropamide(Low Risk)
Acetohexamide(Low Risk)