Question

I am a breastfeeding mother and i want to know if it is safe to use 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin? Is 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin safe for nursing mother and child? Does 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin extracts into breast milk? Does 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin has any long term or short term side effects on infants? Can 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin influence milk supply or can 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin decrease milk supply in lactating mothers?

3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin lactation summary

3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin is safe in breastfeeding
  • DrLact safety Score for 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin usage in lactation

Like most penicillin-type antibiotics, excretion into breast milk is clinically non-significant. No harmful effects have been found among breastfed infants from treated mothers. Widely used for treatment of Mastitis since it has an effective activity against Staphylococcus. Be aware of false negative results of microbial cultures done from samples of febrile infants whose mothers are treated with antibiotics. Also, due to imbalance of intestinal flora a diarrheal disease can occur in the breastfed infant. List of Essential Medicines by WHO 2002: compatible with breastfeeding.

Answer by DrLact: About 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin usage in lactation

Limited information indicates that 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin levels in milk are low and are not expected to cause adverse effects in breastfed infants. It is frequently used to treat mastitis in nursing mothers.[1][2][3] Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with penicillins, but these effects have not been adequately evaluated. 3-(2,6-Dichlorophenyl)-5-methyl-4-isoxazolylpenicillin is acceptable in nursing mothers.

Alternate Drugs

Efavirenz(Unsafe)
Lomefloxacin(Low Risk)
Saquinavir(Unsafe)
Cefaclor(Safe)
Didanosine(Unsafe)
Primaquine(Low Risk)
Levofloxacin(Low Risk)
Nafcillin(Safe)
Atovaquone(Low Risk)
Malathion(Low Risk)
Ritonavir(Unsafe)
Demeclocycline(Low Risk)
Linezolid(Low Risk)
Kanamycin(Safe)
Moxifloxacin(Low Risk)
Cefixime(Safe)
Abacavir(Safe)
Nevirapine(Low Risk)
Naftifine(Safe)
Nelfinavir(Unsafe)
Dapsone(Low Risk)
Cefepime(Safe)
Amikacin(Safe)
Cefprozil(Safe)
Capreomycin(Low Risk)
Famciclovir(Low Risk)
Rifaximin(Safe)
Methicillin(Low Risk)
Ofloxacin(Safe)
Erythromycin(Low Risk)
Indinavir(Unsafe)
Ertapenem(Safe)
Cefdinir(Safe)
Aztreonam(Safe)
Zidovudine(Low Risk)
Clindamycin(Low Risk)
Gatifloxacin(Low Risk)
Cefoxitin(Safe)
Amantadine(Low Risk)
Meropenem(Safe)
Cefazolin(Safe)
Enoxacin(Low Risk)
Econazole(Safe)
Tenofovir(Safe)
Cefotetan(Safe)
Lindane(Unsafe)
Neomycin(Safe)
Acyclovir(Safe)
Valganciclovir(Low Risk)
Doxycycline(Low Risk)
Quinine(Safe)
Ganciclovir(Low Risk)
Levofloxacin(Low Risk)
Nafcillin(Safe)
Demeclocycline(Low Risk)
Cefixime(Safe)
Kanamycin(Safe)
Moxifloxacin(Low Risk)
Cefepime(Safe)
Mupirocin(Safe)
Cefprozil(Safe)
Capreomycin(Low Risk)
Methicillin(Low Risk)
Ofloxacin(Safe)
Erythromycin(Low Risk)
Iodine(Unsafe)
Amikacin(Safe)
Ertapenem(Safe)
Cefdinir(Safe)
Methenamine(Unsafe)
Aztreonam(Safe)
Clindamycin(Low Risk)
Gatifloxacin(Low Risk)
Cefoxitin(Safe)
Cefazolin(Safe)
Enoxacin(Low Risk)
Cefotetan(Safe)
Neomycin(Safe)
Doxycycline(Low Risk)
Lomefloxacin(Low Risk)
Nalidixic Acid(Low Risk)
Cefaclor(Safe)
Nafcillin(Safe)
Methicillin(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.