Question

I am a breastfeeding mother and i want to know if it is safe to use EINECS 221-488-3? Is EINECS 221-488-3 safe for nursing mother and child? Does EINECS 221-488-3 extracts into breast milk? Does EINECS 221-488-3 has any long term or short term side effects on infants? Can EINECS 221-488-3 influence milk supply or can EINECS 221-488-3 decrease milk supply in lactating mothers?

EINECS 221-488-3 lactation summary

EINECS 221-488-3 is safe in breastfeeding
  • DrLact safety Score for EINECS 221-488-3 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of EINECS 221-488-3 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that EINECS 221-488-3 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of EINECS 221-488-3 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About EINECS 221-488-3 usage in lactation

Like most penicillin-type antibiotics, excretion into breast milk is clinically non-significant. No harmful effects have been found among breastfed infants from treated mothers. Widely used for treatment of Mastitis since it has an effective activity against Staphylococcus. Be aware of false negative results of microbial cultures done from samples of febrile infants whose mothers are treated with antibiotics. Also, due to imbalance of intestinal flora a diarrheal disease can occur in the breastfed infant. List of Essential Medicines by WHO 2002: compatible with breastfeeding.

Answer by DrLact: About EINECS 221-488-3 usage in lactation

Limited information indicates that EINECS 221-488-3 levels in milk are low and are not expected to cause adverse effects in breastfed infants. It is frequently used to treat mastitis in nursing mothers.[1][2][3] Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with penicillins, but these effects have not been adequately evaluated. EINECS 221-488-3 is acceptable in nursing mothers.

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Neomycin(Safe)
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Lomefloxacin(Low Risk)
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Amikacin(Safe)
Cefdinir(Safe)
Levofloxacin(Low Risk)
Aztreonam(Safe)
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Cefoxitin(Safe)
Cefazolin(Safe)
Enoxacin(Low Risk)
Kanamycin(Safe)
Moxifloxacin(Low Risk)
Cefotetan(Safe)
Doxycycline(Low Risk)
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Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.