I am a breastfeeding mother and i want to know if it is safe to use Dexlansoprazole? Is Dexlansoprazole safe for nursing mother and child? Does Dexlansoprazole extracts into breast milk? Does Dexlansoprazole has any long term or short term side effects on infants? Can Dexlansoprazole influence milk supply or can Dexlansoprazole decrease milk supply in lactating mothers?

Dexlansoprazole lactation summary

Dexlansoprazole is safe in breastfeeding
  • DrLact safety Score for Dexlansoprazole is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Dexlansoprazole is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Dexlansoprazole does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Dexlansoprazole safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Dexlansoprazole usage in lactation

R Isomer of Lansoprazole with similar pharmacokinetics. At latest update, relevant information on excretion into breast milk was not found. Due to a high serum-protein-binding capacity, excretion of Lansoprazole into breast milk is non-significant. Since it's neutralized by the acid pH of stomach, capsules with enteric coated granules are used. Because of this, it is thought that the small quantity of Lansoprazole that may reach the breast milk would be neutralized by infant's stomach. In addition, absorption is greatly decreased by the presence of food. Both Omeprazole and Pantoprazole pertain to the same chemical group with similar pharmacokinetics that are excreted in non-significant amount into the breast milk. Medication that has been used for treatment of newborn and premature infants. Hyperprolactinemia and galactorrhea have been reported by the use of such medication, though some authors have failed to show the same findings.

Answer by DrLact: About Dexlansoprazole usage in lactation

Dexlansoprazole is the -enantiomer of the protein-pump inhibitor, lansoprazole. No information is available on the use of dexlansoprazole or lansoprazole during breastfeeding. However, lansoprazole has been used safely in newborn infants, so it is unlikely that the amount of dexlansoprazole in breastmilk would be harmful.

Dexlansoprazole Possible Effects in Breastfeeding

One case of elevated serum prolactin and galactorrhea was reported in a 21-year-old man taking lansoprazole (the racemic form). When omeprazole was substituted for lansoprazole, the serum prolactin decreased to the normal range and galactorrhea ceased.[1]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.