Is Endrydil Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Endrydil? Is Endrydil safe for nursing mother and child? Does Endrydil extracts into breast milk? Does Endrydil has any long term or short term side effects on infants? Can Endrydil influence milk supply or can Endrydil decrease milk supply in lactating mothers?
Endrydil lactation summary
- DrLact safety Score for Endrydil is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Endrydil is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Endrydil does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Endrydil safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Endrydil usage in lactation
It is excreted in breast milk in a clinically non-significant amount (Okada 85)Two 6 months-old breastfed twins whose mother was treated with Endrydil did not get into health problems (Lubbe 87) Evidence on other antihypertensive drugs of the same family with similar structure, pharmacokinetics and action profile (nifedipine, nimodipine, nicardipine) has shown that they are excreted into milk in non-significant amount.Endrydil does not have any influence on prolactin production. Until more extensive published data about this drug regarding breastfeeding are available a safer alternative drug should be used, especially during the neonatal period and/or in case of premature infants. American Academy of Pediatrics: medication usually compatible with breastfeeding.
Answer by DrLact: About Endrydil usage in lactation
Based on limited data, amounts of Endrydil ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants.
Alternate Drugs
Labetalol(Safe)
Disopyramide(Safe)
Sotalol(Low Risk)
Amiodarone(Unsafe)
Diltiazem(Safe)
Propranolol(Safe)
Bisoprolol(Low Risk)
Digoxin(Safe)
Quinidine(Safe)
Atenolol(Unsafe)
Propafenone(Low Risk)
Nadolol(Unsafe)
Procainamide(Safe)
Acebutolol(Unsafe)
Flecainide(Safe)
Mexiletine(Safe)
Metoprolol(Safe)
Verapamil(Safe)
Lidocaine(Safe)
Levobunolol(Low Risk)
Timolol(Safe)
Timolol(Safe)
Trandolapril(Dangerous)
Amlodipine(Low Risk)
Nisoldipine(Low Risk)
Torsemide(Low Risk)
Losartan(Low Risk)
Labetalol(Safe)
Sotalol(Low Risk)
Irbesartan(Unsafe)
Isradipine(Low Risk)
Spironolactone(Safe)
Indapamide(Low Risk)
Carvedilol(Low Risk)
Nimodipine(Safe)
Propranolol(Safe)
Diltiazem(Safe)
Reserpine(Unsafe)
Ramipril(Low Risk)
Eprosartan(Low Risk)
Hydrochlorothiazide(Safe)
Bisoprolol(Low Risk)
Bosentan(Low Risk)
Doxazosin(Safe)
Nifedipine(Safe)
Chlorthalidone(Dangerous)
Hydralazine(Safe)
Chlorothiazide(Safe)
Guanfacine(Low Risk)
Furosemide(Low Risk)
Atenolol(Unsafe)
Captopril(Safe)
Fosinopril(Low Risk)
Minoxidil(Safe)
Nadolol(Unsafe)
Bumetanide(Low Risk)
Acebutolol(Unsafe)
Nebivolol(Unsafe)
Metoprolol(Safe)
Valsartan(Low Risk)
Bendroflumethiazide(Unsafe)
Nicardipine(Safe)
Felodipine(Low Risk)
Terazosin(Unsafe)
Methyldopa(Safe)
Benazepril(Safe)
Nitrendipine(Safe)
Verapamil(Safe)
Telmisartan(Unsafe)
Levobunolol(Low Risk)
Enalapril(Safe)
Prazosin(Unsafe)
Lisinopril(Low Risk)
Amlodipine(Low Risk)
Cinnarizine(Low Risk)
Nisoldipine(Low Risk)
Isradipine(Low Risk)
Nimodipine(Safe)
Diltiazem(Safe)
Nifedipine(Safe)
Nicardipine(Safe)
Felodipine(Low Risk)
Nitrendipine(Safe)
Verapamil(Safe)
Isradipine(Low Risk)
Diltiazem(Safe)
Nimodipine(Safe)
Nifedipine(Safe)
Hydralazine(Safe)
Sildenafil(Safe)
Minoxidil(Safe)
Nitroglycerin(Safe)
Nebivolol(Unsafe)
Nicardipine(Safe)
Felodipine(Low Risk)
Verapamil(Safe)
Nitrendipine(Safe)
Amlodipine(Low Risk)
Cinnarizine(Low Risk)
Nisoldipine(Low Risk)