Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-JB937PER5C? Is UNII-JB937PER5C safe for nursing mother and child? Does UNII-JB937PER5C extracts into breast milk? Does UNII-JB937PER5C has any long term or short term side effects on infants? Can UNII-JB937PER5C influence milk supply or can UNII-JB937PER5C decrease milk supply in lactating mothers?

UNII-JB937PER5C lactation summary

UNII-JB937PER5C usage has low risk in breastfeeding
  • DrLact safety Score for UNII-JB937PER5C is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of UNII-JB937PER5C may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that UNII-JB937PER5C may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of UNII-JB937PER5C low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using UNII-JB937PER5C We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About UNII-JB937PER5C usage in lactation

Antihistaminic drug used as treatment of vertigo and dizziness. Sporadic usage is not contraindicated.

Answer by DrLact: About UNII-JB937PER5C usage in lactation

Small, occasional doses of UNII-JB937PER5C would not be expected to cause any adverse effects in breastfed infants. Larger doses or more prolonged use may cause effects in the infant or decrease the milk supply, particularly in combination with a sympathomimetic such as pseudoephedrine or before lactation is well established. Single bedtime doses after the last feeding of the day may be adequate for many women and will minimize any effects of the drug.

UNII-JB937PER5C Side Effects in Breastfeeding

Relevant published information on UNII-JB937PER5C was not found as of the revision date. In one telephone follow-up study, mothers reported irritability and colicky symptoms 10% of infants exposed to various antihistamines and drowsiness was reported in 1.6% of infants. None of the reactions required medical attention. In this study, irritability was reported in one infant of seven exposed to UNII-JB937PER5C in breastmilk.[2]

UNII-JB937PER5C Possible Effects in Breastfeeding

Antihistamines in relatively high doses given by injection can decrease basal serum prolactin in nonlactating women and in early postpartum women.[3][4] However, suckling-induced prolactin secretion is not affected by antihistamine pretreatment of postpartum mothers.[3] Whether lower oral doses of UNII-JB937PER5C have the same effect on serum prolactin or whether the effects on prolactin have any consequences on breastfeeding success have not been studied. The prolactin level in a mother with established lactation may not affect her ability to breastfeed. One woman became dependent on UNII-JB937PER5C during her first pregnancy and continued to take it in a dose of 150 mg daily while she breastfed her infant for 3 months. The infant did well except for a febrile seizure at 2 years of age, which was probably unrelated to UNII-JB937PER5C. During her second pregnancy, she took UNII-JB937PER5C 300 mg daily during the pregnancy and while breastfeeding her infant for 2 years.[5]

Alternate Drugs

Cyclizine(Low Risk)
Meclizine(Low Risk)
Dimenhydrinate(Low Risk)
Doxylamine(Unsafe)
Promethazine(Low Risk)
Droperidol(Low Risk)
Cyclizine(Low Risk)
Diphenhydramine(Low Risk)
Meclizine(Low Risk)
Acrivastine(Low Risk)
Epinastine(Low Risk)
Dimenhydrinate(Low Risk)
Levocetirizine(Low Risk)
Pyrilamine(Low Risk)
Doxylamine(Unsafe)
Clemastine(Low Risk)
Ketotifen(Low Risk)
Carbinoxamine(Low Risk)
Brompheniramine(Low Risk)
Azelastine(Low Risk)
Cimetidine(Low Risk)
Cascara Sagrada(Low Risk)
Dimenhydrinate(Low Risk)
Bisacodyl(Safe)
Doxylamine(Unsafe)
Ursodiol(Safe)
Droperidol(Low Risk)
Senna(Safe)
Rifaximin(Safe)
Alosetron(Low Risk)
Cisapride(Safe)
Cyclizine(Low Risk)
Docusate(Safe)

Synonyms of UNII-JB937PER5C

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