Is H 3292 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use H 3292? Is H 3292 safe for nursing mother and child? Does H 3292 extracts into breast milk? Does H 3292 has any long term or short term side effects on infants? Can H 3292 influence milk supply or can H 3292 decrease milk supply in lactating mothers?
H 3292 lactation summary
- DrLact safety Score for H 3292 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of H 3292 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that H 3292 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of H 3292 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About H 3292 usage in lactation
American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.
Answer by DrLact: About H 3292 usage in lactation
H 3292 is sometimes found in the plasma of nursing infants at levels of 7.5-12.5% of the mother's levels. The N-monodesalkylH 3292 (NMD) metabolite is more anticholinergic than H 3292 itself and appears in breastmilk in levels higher than H 3292. However, of the cases reported, there are no reports of infant effects. H 3292 may be used cautiously while breastfeeding when other alternatives are unacceptable. Observe the infant for anticholinergic symptoms. Infant serum concentrations can be monitored if there is any concern about drug-induced adverse effects. Theoretically, H 3292 might decrease the milk supply.
H 3292 Side Effects in Breastfeeding
There are reports of 2 infants who were breastfed without complications during maternal H 3292 use of 500 to 600 mg daily.[1][2] Infant symptoms of crying and restlessness after meals thought by one mother to be caused by H 3292 in breastmilk were judged to be unrelated by the examining physicians.[3]
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