Is EINECS 223-110-2 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use EINECS 223-110-2? Is EINECS 223-110-2 safe for nursing mother and child? Does EINECS 223-110-2 extracts into breast milk? Does EINECS 223-110-2 has any long term or short term side effects on infants? Can EINECS 223-110-2 influence milk supply or can EINECS 223-110-2 decrease milk supply in lactating mothers?
EINECS 223-110-2 lactation summary
- DrLact safety Score for EINECS 223-110-2 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of EINECS 223-110-2 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that EINECS 223-110-2 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of EINECS 223-110-2 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About EINECS 223-110-2 usage in lactation
American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.
Answer by DrLact: About EINECS 223-110-2 usage in lactation
EINECS 223-110-2 is sometimes found in the plasma of nursing infants at levels of 7.5-12.5% of the mother's levels. The N-monodesalkylEINECS 223-110-2 (NMD) metabolite is more anticholinergic than EINECS 223-110-2 itself and appears in breastmilk in levels higher than EINECS 223-110-2. However, of the cases reported, there are no reports of infant effects. EINECS 223-110-2 may be used cautiously while breastfeeding when other alternatives are unacceptable. Observe the infant for anticholinergic symptoms. Infant serum concentrations can be monitored if there is any concern about drug-induced adverse effects. Theoretically, EINECS 223-110-2 might decrease the milk supply.
EINECS 223-110-2 Side Effects in Breastfeeding
There are reports of 2 infants who were breastfed without complications during maternal EINECS 223-110-2 use of 500 to 600 mg daily.[1][2] Infant symptoms of crying and restlessness after meals thought by one mother to be caused by EINECS 223-110-2 in breastmilk were judged to be unrelated by the examining physicians.[3]
Alternate Drugs
Atenolol(Unsafe)
Acebutolol(Unsafe)
Verapamil(Safe)
Lidocaine(Safe)
Quinidine(Safe)
Timolol(Safe)
Propafenone(Low Risk)
Sotalol(Low Risk)
Procainamide(Safe)
Propranolol(Safe)
Mexiletine(Safe)
Flecainide(Safe)
Disopyramide(Safe)
Nadolol(Unsafe)
Diltiazem(Safe)
Metoprolol(Safe)
Digoxin(Safe)
Amiodarone(Unsafe)
Levobunolol(Low Risk)
Labetalol(Safe)
Bisoprolol(Low Risk)