Is Searle 703 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Searle 703? Is Searle 703 safe for nursing mother and child? Does Searle 703 extracts into breast milk? Does Searle 703 has any long term or short term side effects on infants? Can Searle 703 influence milk supply or can Searle 703 decrease milk supply in lactating mothers?
Searle 703 lactation summary
- DrLact safety Score for Searle 703 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Searle 703 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Searle 703 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Searle 703 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Searle 703 usage in lactation
American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.
Answer by DrLact: About Searle 703 usage in lactation
Searle 703 is sometimes found in the plasma of nursing infants at levels of 7.5-12.5% of the mother's levels. The N-monodesalkylSearle 703 (NMD) metabolite is more anticholinergic than Searle 703 itself and appears in breastmilk in levels higher than Searle 703. However, of the cases reported, there are no reports of infant effects. Searle 703 may be used cautiously while breastfeeding when other alternatives are unacceptable. Observe the infant for anticholinergic symptoms. Infant serum concentrations can be monitored if there is any concern about drug-induced adverse effects. Theoretically, Searle 703 might decrease the milk supply.
Searle 703 Side Effects in Breastfeeding
There are reports of 2 infants who were breastfed without complications during maternal Searle 703 use of 500 to 600 mg daily.[1][2] Infant symptoms of crying and restlessness after meals thought by one mother to be caused by Searle 703 in breastmilk were judged to be unrelated by the examining physicians.[3]
Alternate Drugs
Disopyramide(Safe)
Nadolol(Unsafe)
Diltiazem(Safe)
Metoprolol(Safe)
Digoxin(Safe)
Levobunolol(Low Risk)
Amiodarone(Unsafe)
Labetalol(Safe)
Bisoprolol(Low Risk)
Atenolol(Unsafe)
Acebutolol(Unsafe)
Verapamil(Safe)
Lidocaine(Safe)
Quinidine(Safe)
Timolol(Safe)
Propafenone(Low Risk)
Sotalol(Low Risk)
Procainamide(Safe)
Propranolol(Safe)
Mexiletine(Safe)
Flecainide(Safe)