Is 5-Hydroxy-alpha-6-deoxytetracycline Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use 5-Hydroxy-alpha-6-deoxytetracycline? Is 5-Hydroxy-alpha-6-deoxytetracycline safe for nursing mother and child? Does 5-Hydroxy-alpha-6-deoxytetracycline extracts into breast milk? Does 5-Hydroxy-alpha-6-deoxytetracycline has any long term or short term side effects on infants? Can 5-Hydroxy-alpha-6-deoxytetracycline influence milk supply or can 5-Hydroxy-alpha-6-deoxytetracycline decrease milk supply in lactating mothers?

Excreted into breast milk in quantities that would be clinically significant, however, intestinal absorption by infant's gut is hampered because of formation of chelating products by union with the milk's calcium. Tetracycline is at lesser amount excreted into breast milk and at higher proportion bound to calcium, hence, it is fewer absorbed than 5-Hydroxy-alpha-6-deoxytetracycline. Thus, it is a optimal alternative while breastfeeding. Long-term treatments are not recommended (over 3-4 weeks) since it may cause damage of the growth cartilage, teeth discoloration and imbalance of intestinal flora. Be aware of false negative results that may be obtained from infants with bacterial cultures when the mother is on antibiotics.

A number of reviews have stated that tetracyclines are contraindicated during breastfeeding because of possible staining of infants' dental enamel or bone deposition of tetracyclines. However, a close examination of available literature indicates that there is not likely to be harm in short-term use of 5-Hydroxy-alpha-6-deoxytetracycline during lactation because milk levels are low and absorption by the infant is inhibited by the calcium in breastmilk. Short-term use of 5-Hydroxy-alpha-6-deoxytetracycline is acceptable in nursing mothers. As a theoretical precaution, avoid prolonged or repeat courses during nursing. Monitor the infant for rash and for possible effects on the gastrointestinal flora, such as diarrhea or candidiasis (thrush, diaper rash).