Question

I am a breastfeeding mother and i want to know if it is safe to use Brinzolamide? Is Brinzolamide safe for nursing mother and child? Does Brinzolamide extracts into breast milk? Does Brinzolamide has any long term or short term side effects on infants? Can Brinzolamide influence milk supply or can Brinzolamide decrease milk supply in lactating mothers?

Brinzolamide lactation summary

Brinzolamide usage has low risk in breastfeeding
  • DrLact safety Score for Brinzolamide is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Brinzolamide may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Brinzolamide may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Brinzolamide low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Brinzolamide We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Brinzolamide usage in lactation

It is a carbonic anhydrase (CA) inhibitor sulphonamide drug which is used as 1% drops for topical treatment to lower intraocular pressure or glaucoma. EMEA and FDA have informed of very low serum levels found to be bound to CA red blood cells even after oral ingestion. For this reason and because it is usually used as a topical treatment its presence in mother’s milk is unlikely. Like most ophthalmologic compounds for topical use, a low dose and poor absorption make it compatible with breastfeeding. Pressing conjunctiva sack for a couple of minutes to lessen systemic absorption.

Answer by DrLact: About Brinzolamide usage in lactation

Because no information is available on the use of brinzolamide during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.