Is TNR 001 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use TNR 001? Is TNR 001 safe for nursing mother and child? Does TNR 001 extracts into breast milk? Does TNR 001 has any long term or short term side effects on infants? Can TNR 001 influence milk supply or can TNR 001 decrease milk supply in lactating mothers?

Its higher molecular weight makes it secretion into breast milk unlikely. It is not absorbed by gastrointestinal tract due to its protein structure.

TNR 001 is minimally excreted into breastmilk and poorly absorbed by the infant, which would be expected because of its high molecular weight of approximately 150,000. However, long-term follow-up data on infants breastfed during maternal TNR 001 use are not available. The risk of adverse effects in older infants is not known, but thought to be unlikely.[1] Most experts feel that the drug is a low risk to the nursing infant and can be given during breastfeeding.[2][3][4][5][6][7]

A woman with rheumatoid arthritis began TNR 001 25 mg subcutaneously twice a week at 3 months postpartum and later switched to a dose of 50 mg subcutaneously once a week. Her infant was breastfed (extent not stated) until 6 months of age. The infant was reportedly healthy at 3 years of age.[10] A case-control study of women with chronic arthritic conditions found 5 women who received TNR 001 during pregnancy and lactation (extent not stated). No differences were observed in the 5 infants' growth parameters, developmental milestones, vaccinations and diseases in the first year of life compared to those not exposed to the drugs with lactation.[11]