Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-M5DP350VZV? Is UNII-M5DP350VZV safe for nursing mother and child? Does UNII-M5DP350VZV extracts into breast milk? Does UNII-M5DP350VZV has any long term or short term side effects on infants? Can UNII-M5DP350VZV influence milk supply or can UNII-M5DP350VZV decrease milk supply in lactating mothers?

UNII-M5DP350VZV lactation summary

UNII-M5DP350VZV usage has low risk in breastfeeding
  • DrLact safety Score for UNII-M5DP350VZV is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of UNII-M5DP350VZV may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that UNII-M5DP350VZV may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of UNII-M5DP350VZV low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using UNII-M5DP350VZV We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About UNII-M5DP350VZV usage in lactation

Loop diuretic. Long-term treatment with diuretic drugs (particularly those Thiazides with long lasting effect and loop-acting drugs) may inhibit lactation. Use a lower dose as possible, especially during the first postnatal month.

Answer by DrLact: About UNII-M5DP350VZV usage in lactation

Because no information is available on the use of UNII-M5DP350VZV during breastfeeding and because intense diuresis might decrease lactation, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

UNII-M5DP350VZV Possible Effects in Breastfeeding

UNII-M5DP350VZV was reportedly used successfully to suppress lactation in 6 postpartum women who did not want to breastfeed and to decrease the intensity of milk production in another.[1] The added contribution of the diuretic to the other measures, which are effective in suppressing lactation, has not been studied. No data exist on the effects of loop diuretics on established, ongoing lactation.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.